Research

  • Genomic diversity of Leishmania single-cell tropical parasites isolated from infected people and animals
  • Control of gene activity in methicillin-resistant Staphylococcus aureus (MRSA) during exposure to drug treatments
  • Genetic variation of Escherichia coli ST131 infections and the associated spread of antimicrobial resistance.

We tackle these areas using genomics, population genetics and systems biology approaches, with a particular long-term aim of understanding the evolutionary roles of recombination, hybridization and population admixture. These microbes in-focus evolve resistance to drugs by changing their DNA, and these potent mutations spread by mixing.

 

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