- Genomic diversity of Leishmania single-cell tropical parasites isolated from infected people and animals
- Control of gene activity in methicillin-resistant Staphylococcus aureus (MRSA) during exposure to drug treatments
- Genetic variation of Escherichia coli ST131 infections and the associated spread of antimicrobial resistance.
We tackle these areas using genomics, population genetics and systems biology approaches, with a particular long-term aim of understanding the evolutionary roles of recombination, hybridization and population admixture. These microbes in-focus evolve resistance to drugs by changing their DNA, and these potent mutations spread by mixing.